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The British Journal of Diabetes & Vascular Disease
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Reviews

Review: Heart failure complicating acute myocardial infarction in patients with diabetes: pathophysiology and management strategies

Sreekumar Sulfi

Department of Cardiology, London Chest Hospital, London, E2 9JX

Adam D Timmis

Department of Cardiology, London Chest Hospital, London, E2 9JX, adamtimmis{at}mac.com

iabetes mellitus increases the risk of acute coronary events and is similar to that of people without diabetes who have experienced a myocardial infarction (MI). Left ventricular failure is a major contributor to the excess mortality observed in diabetic MI. This review explores this excess risk and considers strategies for its prevention and treatment.

Key Words: diabetes mellitus • myocardial infarction • heart failure • management.

References

  • Haffner SM, Lehto S., Ronnemaa T., Pyorala K., Laakso M. Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction. N Engl J Med 1998;339:229-34.[Abstract/Free Full Text]
  • Wild S., Roglic G., Green A., Sicree R., King H. Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care 2004;27:1047-53.[Abstract/Free Full Text]
  • Aguilar D., Solomon SD, Kober L. et al. Newly diagnosed and previously known diabetes mellitus and 1-year outcomes of acute myocardial infarction: the VALsartan In Acute myocardial iNfarcTion (VALIANT) trial. Circulation 2004;110:1572-8.[Abstract/Free Full Text]
  • Mukamal KJ, Nesto RW, Cohen MC et al. Impact of diabetes on longterm survival after acute myocardial infarction: comparability of risk with prior myocardial infarction. Diabetes Care 2001;24:1422-7.[Abstract/Free Full Text]
  • Franklin K., Goldberg RJ, Spencer F. et al. Implications of diabetes in patients with acute coronary syndromes. The Global Registry of Acute Coronary Events. Arch Intern Med 2004;164:1457-63.of insulin-glucose[Abstract/Free Full Text]
  • Malmberg K., Ryden L., Efendic S. et al. Randomized trial of insulin-glucose infusion followed by subcutaneous insulin treatment in diabetic patients with acute myocardial infarction (DIGAMI study): effects on mortality at 1 year. J Am Coll Cardiol 1995;26:57-65.[Abstract]
  • Malmberg K., Yusuf S., Gerstein HC et al. Impact of diabetes on long-term prognosis in patients with unstable angina and non-Q-wave myocardial infarction: results of the OASIS (Organization to Assess Strategies for Ischemic Syndromes) Registry. Circulation 2000;102:1014-19.[Abstract/Free Full Text]
  • Orlander PR, Goff DC, Morrissey M. et al. The relation of diabetes to the severity of acute myocardial infarction and post-myocardial infarction survival in Mexican-Americans and non-Hispanic whites. The Corpus Christi Heart Project. Diabetes 1994;43:897-902.[Abstract]
  • Stone PH, Muller JE, Hartwell T. et al. The effect of diabetes mellitus on prognosis and serial left ventricular function after acute myocardial infarction: contribution of both coronary disease and diastolic left ventricular dysfunction to the adverse prognosis. The MILIS Study Group. J Am Coll Cardiol 1989;14:49-57.[Abstract]
  • Melchior T., Rask-Madsen C., Torp-Pedersen C., Hildebrandt P., Kober L., Jensen G. The impact of heart failure on prognosis of diabetic and non-diabetic patients with myocardial infarction: a 15-year follow-up study. Eur J Heart Fail 2001;3:83-90.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • Foo K., Sekhri N., Deaner A. et al. Effect of diabetes on serum potassium concentrations in acute coronary syndromes. Heart 2003;89:31-5.[Abstract/Free Full Text]
  • Culic V., Eterovic D., Miric D., Silic N. Symptom presentation of acute myocardial infarction: influence of sex, age, and risk factors. Am Heart J 2002;144:1012-17.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • Canto JG, Shlipak MG, Rogers WJ et al. Prevalence, clinical characteristics, and mortality among patients with myocardial infarction presenting without chest pain. JAMA 2000;283:3223-9.[Abstract/Free Full Text]
  • Airaksinen KE Silent coronary artery disease in diabetes - a feature of autonomic neuropathy or accelerated atherosclerosis? Diabetologia 2001;44:259-66.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • Ottesen MM, Kober L., Jorgensen S., Torp-Pedersen C. Determinants of delay between symptoms and hospital admission in 5978 patients with acute myocardial infarction. The TRACE Study Group. Trandolapril Cardiac Evaluation. Eur Heart J 1996;17:429-37.[Abstract/Free Full Text]
  • Sutton MGS, Sharpe N. Left Ventricular Remodeling After Myocardial Infarction:Pathophysiology and Therapy. Circulation 2000;101:2981-8.[Free Full Text]
  • Pfeffer MA, Braunwald E. Ventricular remodeling after myocardial infarction. Experimental observations and clinical implications. Circulation 1990;81:1161-72.[Abstract/Free Full Text]
  • Iwasaka T., Takahashi N., Nakamura S. et al. Residual left ventricular pump function after acute myocardial infarction in NIDDM patients. Diabetes Care 1992;15:1522-6.[Abstract]
  • Solomon SD, St John SM, Lamas GA et al. Ventricular remodeling does not accompany the development of heart failure in diabetic patients after myocardial infarction. Circulation 2002;106:1251-5.[Abstract/Free Full Text]
  • Dini FL, Volterrani C., Azzarelli A. et al. Left ventricular size and function in patients with noninsulin-dependent diabetes and postinfarction total or subtotal coronary occlusions. Angiology 1998;49:967-73.[Medline] [Order article via Infotrieve]
  • Carrabba N., Valenti R., Parodi G., Santoro GM, Antoniucci D. Left ventricular remodeling and heart failure in diabetic patients treated with primary angioplasty for acute myocardial infarction. Circulation 2004;110: 1974-9.[Abstract/Free Full Text]
  • Boyer JK, Thanigaraj S., Schechtman KB, Perez JE Prevalence of ventricular diastolic dysfunction in asymptomatic, normotensive patients with diabetes mellitus. Am J Cardiol 2004;93:870-5.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • Zabalgoitia M., Ismaeil MF, Anderson L., Maklady FA Prevalence of diastolic dysfunction in normotensive, asymptomatic patients with well-controlled type 2 diabetes mellitus. Am J Cardiol 2001;87:320-3.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • Fang ZY, Schull-Meade R., Leano R., Mottram PM, Prins JB, Marwick TH Screening for heart disease in diabetic subjects. Am Heart J 2005;149:349-54.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • Di B.V., Talarico L., Picano E. et al. Increased echodensity of myocardial wall in the diabetic heart: an ultrasound tissue characterization study. J Am Coll Cardiol 1995;25:1408-15.[Abstract]
  • Perez JE, McGill JB, Santiago JV et al. Abnormal myocardial acoustic properties in diabetic patients and their correlation with the severity of disease. J Am Coll Cardiol 1992;19:1154-62.[Abstract]
  • Granger CB, Califf RM, Young S. et al. Outcome of patients with diabetes mellitus and acute myocardial infarction treated with thrombolytic agents. The Thrombolysis and Angioplasty in Myocardial Infarction (TAMI) Study Group. J Am Coll Cardiol 1993;21:920-5.[Abstract]
  • Vinereanu D., Nicolaides E., Tweddel AC et al. Subclinical left ventricular dysfunction in asymptomatic patients with type II diabetes mellitus, related to serum lipids and glycated haemoglobin. Clin Sci (Lond) 2003;105:591-9.[Medline] [Order article via Infotrieve]
  • Fang ZY, Yuda S., Anderson V., Short L., Case C., Marwick TH Echocardiographic detection of early diabetic myocardial disease. J Am Coll Cardiol 2003;41:611-17.[Abstract/Free Full Text]
  • Kannel WB, Hjortland M., Castelli WP Role of diabetes in congestive heart failure: the Framingham study. Am J Cardiol 1974;34:29-34.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • Rubler S., Dlugash J., Yuceoglu YZ, Kumral T., Branwood AW, Grishman A. New type of cardiomyopathy associated with diabetic glomerulosclerosis. Am J Cardiol 1972;30:595-602.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • Hardin NJ The myocardial and vascular pathology of diabetic cardiomyopathy. Coron Artery Dis 1996;7:99-108.[Web of Science][Medline] [Order article via Infotrieve]
  • Di Carli MF, Bianco-Batlles D., Landa ME et al. Effects of autonomic neuropathy on coronary blood flow in patients with diabetes mellitus. Circulation 1999 Aug 24;100:813-19.
  • Foo K., Sekhri N., Knight C. et al. The effect of diabetes on heart rate and other determinants of myocardial oxygen demand in acute coronary syndromes. Diabet Med 2004;21:1025-31.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • Bell DS Heart failure: the frequent, forgotten, and often fatal complication of diabetes. Diabetes Care 2003;26:2433-41.[Abstract/Free Full Text]
  • Oliver MF, Opie LH Effects of glucose and fatty acids on myocardial ischaemia and arrhythmias. Lancet 1994;343:155-8.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • Williams IL, Noronha B., Zaman AG The management of acute myocardial infarction in patients with diabetes mellitus. Br J Diabetes Vasc Dis 2003;3:319-24.[Abstract/Free Full Text]
  • Pfeffer MA, Moye LA, Braunwald E. et al. Selection bias in the use of thrombolytic therapy in acute myocardial infarction. The SAVE Investigators. JAMA 1991;266:528-32.[Abstract/Free Full Text]
  • Shotliff K., Kaushal R., Dove D., Nussey SS Withholding thrombolysis in patients with diabetes mellitus and acute myocardial infarction. Diabet Med 1998;15:1028-30.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • Younis N., Burnham P., Patwala A., Weston PJ, Vora JP Beta blocker prescribing differences in patients with and without diabetes following a first myocardial infarction. Diabet Med 2001;18:159-61.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • Randomised trial of intravenous streptokinase, oral aspirin, both, or neither among 17,187 cases of suspected acute myocardial infarction: ISIS-2. ISIS-2 (Second International Study of Infarct Survival) Collaborative Group. Lancet 1988;2:349-60.[Medline] [Order article via Infotrieve]
  • Goldberg RB, Mellies MJ, Sacks FM et al. Cardiovascular events and their reduction with pravastatin in diabetic and glucose-intolerant myocardial infarction survivors with average cholesterol levels: subgroup analyses in the cholesterol and recurrent events (CARE) trial. The Care Investigators. Circulation 1998;98:2513-19.[Abstract/Free Full Text]
  • Ingelsson E., Sundstrom J., Arnlov J., Zethelius B., Lind L. Insulin resistance and risk of congestive heart failure. JAMA 2005;294:334-41.[Abstract/Free Full Text]
  • Wison S., Foo K., Cunningham J. et al. Renal function and risk stratification in acute coronary syndromes. Am J Cardiol 2003;91:1051-4.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • Archbold RA, Balami D., Al-Hajiri A. et al. Haemoglobin concentration is an independent determinant of heart failure in acute coronary syndromes: cohort analysis of 2310 patients. Am Heart J 2006;in press.
  • Indications for fibrinolytic therapy in suspected acute myocardial infarction: collaborative overview of early mortality and major morbidity results from all randomised trials of more than 1000 patients. Fibrinolytic Therapy Trialists' (FTT) Collaborative Group. Lancet 1994;343:311-22.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • Farkouh ME, Ramanathan K., Aymong ED et al. An early revascularization strategy is associated with a survival benefit for diabetic patients in cardiogenic shock after acute myocardial infarction. Clin Cardiol 2006;29:204-10.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • Fath-Ordoubadi F., Beatt KJ Glucose-insulin-potassium therapy for treatment of acute myocardial infarction: an overview of randomized placebo-controlled trials. Circulation 1997;96:1152-6.[Abstract/Free Full Text]
  • Malmberg K., Ryden L., Wedel H. et al. Intense metabolic control by means of insulin in patients with diabetes mellitus and acute myocardial infarction (DIGAMI 2): effects on mortality and morbidity. Eur Heart J 2005;26: 650-61.[Abstract/Free Full Text]
  • Nesto RW, Zarich S. Acute myocardial infarction in diabetes mellitus: lessons learned from ACE inhibition. Circulation 1998;97:12-15.[Free Full Text]
  • Rutherford JD, Pfeffer MA et al. Effects of captopril on ischemic events after myocardial infarction. Results of the Survival and Ventricular Enlargement trial. SAVE Investigators. Circulation 1994;90:1731-8.[Abstract/Free Full Text]
  • Effects of ramipril on cardiovascular and microvascular outcomes in people with diabetes mellitus: results of the HOPE study and MICRO-HOPE substudy. Heart Outcomes Prevention Evaluation Study Investigators. Lancet 2000;355:253-9.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • Zuanetti G., Latini R., Maggioni AP, Franzosi M., Santoro L., Tognoni G. Effect of the ACE inhibitor lisinopril on mortality in diabetic patients with acute myocardial infarction: data from the GISSI-3 study. Circulation 1997;96:4239-45.[Abstract/Free Full Text]

The British Journal of Diabetes & Vascular Disease, Vol. 6, No. 5, 191-196 (2006)
DOI: 10.1177/14746514060060050201
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This Article
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