|
Sign In to gain access to subscriptions and/or personal tools.
|
Review: Physical disability and the cumulative impact of diabetes in older adults
Edward W Gregg
Division of Diabetes Translation, Centers for Disease Control and Prevention, 4770 Buford Highway, NE Mailstop K-10, Atlanta, GA 30341, USA, edg7{at}cdc.gov
Carl J Caspersen
Division of Diabetes Translation, Centers for Disease Control and Prevention, 4770 Buford Highway, NE Mailstop K-10, Atlanta, GA 30341, USA
he already high and increasing prevalence of diabetes among older adults will make ageing-related outcomes like physical disability an increasingly important complication of diabetes. Disability is a key indicator of both overall morbidity and the success of public health efforts to compress the period of morbidity in old age for the overall population. Many cross-sectional and longitudinal studies have now associated diabetes with increased risk of disabilities in mobility and in instrumental and basic activities of living. The explanation for higher disability among persons with diabetes appears to be multifactorial with neuropathy, peripheral arterial disease, coronary heart disease, depression, obesity, visual impairment, and physical inactivity the most prominent factors. These factors are common in persons with diabetes and exert strong effects on risk of disability. Several promising interventions exist, ranging from exercise programmes and identification and treatment of depression, to long-term prevention of disability through better management of glycaemia and risk factors for cardiovascular disease. Preliminary findings from the U.S. Diabetes Surveillance System suggest that, like the general population, prevalence of physical disability may also have declined among persons with diabetes during the last decade. Ultimately, preventing disability will likely depend on a combination of secondary and tertiary prevention along with, ideally, preventing diabetes in the first place.
Key Words: diabetes mellitus disability functional limitations mobility morbidity.
References
- Engelgau MM, Geiss LS, Saaddine JB et al. The evolving diabetes burden in the United States. Ann Intern Med 2004;140:945-50.[Abstract/Free Full Text]
- . Centers for Disease Control and Prevention. Prevalence of diabetes and impaired fasting glucose in adults - United States, 1999-2000. MMWR Morb Mortal Wkly Rep 2003;52:833-7.[Medline]
[Order article via Infotrieve]
- DECODE Study Group. Age- and sex-specific prevalences of diabetes and impaired glucose regulation in 13 European cohorts. Diabetes Care 2003;26:61-9.[Abstract/Free Full Text]
- Sinclair AJ, Gadsby R., Penfold S., Croxson SC, Bayer AJ Prevalence of diabetes in care home residents. Diabetes Care 2001;24:1066-8.[Abstract/Free Full Text]
- Boyle JP, Honeycutt AA, Narayan KM et al. Projection of diabetes burden through 2050: impact of changing demography and disease prevalence in the U.S. Diabetes Care 2001;24:1936-40.[Abstract/Free Full Text]
- Wild S., Roglic G., Green A., Sicree R., King H. Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care 2004;27:1047-53.[Abstract/Free Full Text]
- Narayan KM, Gregg EW, Fagot-Campagna A., Engelgau MM, Vinicor F. Diabetes - a common, growing, serious, costly, and potentially preventable public health problem. Diabetes Res Clin Pract 2000;50(suppl 2):S77-S84.[CrossRef][Web of Science][Medline]
[Order article via Infotrieve]
- Gregg EW, Engelgau MM, Narayan V. Complications of diabetes in elderly people. BMJ 2002;325:916-17.[Free Full Text]
- Katz, S., Ford AB, Moskowitz RW, Jackson BA, Jaffe MW Studies of illness in the aged. The index of ADL: A standardized measure of biological and psychosocial function. JAMA 1963;185:914-19.[Abstract/Free Full Text]
- Lawton MP, Brody EM Assessment of older people: self-maintaining and instrumental activities of daily living. Gerontologist 1969;9:179-86.[Web of Science][Medline]
[Order article via Infotrieve]
- de Rekeneire N., Resnick HE, Schwartz AV et al. Diabetes is associated with subclinical functional limitation in nondisabled older individuals: the Health, Aging, and Body Composition study. Diabetes Care 2003; 26:3257-63.[Abstract/Free Full Text]
- Guralnik JM, Fried LP, Salive ME Disability as a public health outcome in the aging population. Annu Rev Public Health 1996;17:25-46.[CrossRef][Web of Science][Medline]
[Order article via Infotrieve]
- Reuben DB, Seeman TE, Keeler et al. Refining the categorization of physical functional status: the added value of combining self-reported and performance-based measures. J Gerontol A Biol Sci Med Sci 2004;59: M1056-M1061.[Abstract/Free Full Text]
- Fried LP, Bush TL Morbidity as a focus of preventive health care in the elderly. Epidemiol Rev 1988;10:48-64.[Free Full Text]
- Phelan EA, Anderson LA, LaCroix AZ, Larson EB Older adults' views of `successful aging` - how do they compare with researchers' definitions? J Am Geriatr Soc 2004;52:211-16.[CrossRef][Web of Science][Medline]
[Order article via Infotrieve]
- Fries JF Measuring and monitoring success in compressing morbidity. Ann Intern Med 2003;139:455-9.[Abstract/Free Full Text]
- Crimmins EM Trends in the health of the elderly. Annu Rev Public Health 2004;25:79-98.[CrossRef][Web of Science][Medline]
[Order article via Infotrieve]
- Thomas RJ, Palumbo PJ, Melton LJ, III et al. Trends in the mortality burden associated with diabetes mellitus: a population-based study in Rochester, Minn, 1970-1994. Arch Intern Med 2003;163:445-51.[Abstract/Free Full Text]
- Fox CS, Coady S., Sorlie PD et al. Trends in cardiovascular complications of diabetes. JAMA 2004;292:2495-9.[Abstract/Free Full Text]
- Tierney EF, Cadwell BL, Engelgau MM et al. Declining mortality rate among people with diabetes in North Dakota, 1997-2002. Diabetes Care 2004;27:2723-5.[Free Full Text]
- Gregg EW, Beckles GL, Williamson DF et al. Diabetes and physical disability among older U.S. adults. Diabetes Care 2000;23:1272-7.[Abstract/Free Full Text]
- Ryerson B., Tierney EF, Thompson TJ et al. Excess physical limitations among adults with diabetes in the U.S. population, 1997-1999. Diabetes Care 2003;26:206-10.[Abstract/Free Full Text]
- Volpato S., Blaum C., Resnick H., Ferrucci L., Fried LP, Guralnik JM Comorbidities and impairments explaining the association between diabetes and lower extremity disability: The Women's Health and Aging Study. Diabetes Care 2002;25:678-83.[Abstract/Free Full Text]
- Ferrucci L., Penninx BW, Leveille SG et al. Characteristics of nondisabled older persons who perform poorly in objective tests of lower extremity function. J Am Geriatr Soc 2000;48:1102-10.[Web of Science][Medline]
[Order article via Infotrieve]
- Maty SC, Fried LP, Volpato S., Williamson J., Brancati FL, Blaum CS Patterns of disability related to diabetes mellitus in older women. J Gerontol A Biol Sci Med Sci 2004;59:148-53.[Web of Science][Medline]
[Order article via Infotrieve]
- Miller DK, Lui LY, Perry HM, III, Kaiser FE, Morley JE Reported and measured physical functioning in older inner-city diabetic African Americans. J Gerontol A Biol Sci Med Sci 1999;54:M230-M236.[Abstract]
- Gregg EW, Mangione CM, Cauley JA et al. Diabetes and incidence of functional disability in older women. Diabetes Care 2002;25:61-7.[Abstract/Free Full Text]
- Volpato S., Ferrucci L., Blaum C. et al. Progression of lower-extremity disability in older women with diabetes: the Women's Health and Aging Study. Diabetes Care 2003;26:70-5. 29. 9. Hardy SE, Gill TM Recovery from disability among community-dwelling older persons. JAMA 2004;291:1596-602.[Abstract/Free Full Text]
- Clark DO, Stump TE, Hui SL, Wolinsky FD Predictors of mobility and basic ADL difficulty among adults aged 70 years and older. J Aging Health 1998;10:422-40.[Abstract/Free Full Text]
- Freedman VA, Martin LG, Schoeni RF Recent trends in disability and functioning among older adults in the United States: a systematic review. JAMA 2002;288:3137-46.[Abstract/Free Full Text]
- Centers for Disease Control and Prevention. Diabetes Surveillance System: Poor mental health, poor mental or physical health, and inability to do usual activities. Diabetes Surveillance System 2004. www.cdc.gov/diabetes/statistics/mental/indexUS.htm.lastaccessed 11/27/ 2004.
- Centers for Disease Control and Prevention. Diabetes Surveillance System: Poor mental health, poor mental or physical health, and inability to do usual activities. Diabetes Surveillance System 2004. www.cdc.gov/diabetes/statistics/mobility/table4link.htm.lastaccessed 11/27/2004.
- Guralnik JM, Ferrucci L., Balfour JL, Volpato S., Di Iorio A. Progressive versus catastrophic loss of the ability to walk: implications for the prevention of mobility loss. J Am Geriatr Soc 2001;49:1463-70.[CrossRef][Web of Science][Medline]
[Order article via Infotrieve]
- McDermott MM, Liu K., Greenland P. et al. Functional decline in peripheral arterial disease: associations with the ankle brachial index and leg symptoms. JAMA 2004;292:453-61.[Abstract/Free Full Text]
- Dolan NC, Liu K., Criqui MH et al. Peripheral artery disease, diabetes, and reduced lower extremity functioning. Diabetes Care 2002;25:113-20.[Abstract/Free Full Text]
- Resnick HE, Stansberry KB, Harris TB et al. Diabetes, peripheral neuropathy, and old age disability. Muscle Nerve 2002;25:43-50.[CrossRef][Web of Science][Medline]
[Order article via Infotrieve]
- Klein R., Klein BE Relation of glycemic control to diabetic complications and health outcomes. Diabetes Care 1998;21(suppl 3):C39-C43.[Web of Science][Medline]
[Order article via Infotrieve]
- Black SA Increased health burden associated with comorbid depression in older diabetic Mexican Americans. Results from the Hispanic Established Population for the Epidemiologic Study of the Elderly survey. Diabetes Care 1999;22:56-64.[Abstract/Free Full Text]
- Klein BE, Klein R., Moss SE Self-rated health and diabetes of long duration. The Wisconsin Epidemiologic Study of Diabetic Retinopathy. Diabetes Care 1998;21:236-40.[Abstract]
- Mitchell BD, Stern MP, Haffner SM, Hazuda HP, Patterson JK Functional impairment in Mexican Americans and non-Hispanic whites with diabetes. J Clin Epidemiol 1990;43:319-27.[CrossRef][Web of Science][Medline]
[Order article via Infotrieve]
- Fried LP, Tangen CM, Walston J. et al. Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci 2001;56:M146-M156.[Abstract/Free Full Text]
- Penninx BW, Messier SP, Rejeski WJ et al. Physical exercise and the prevention of disability in activities of daily living in older persons with osteoarthritis. Arch Intern Med 2001;161:2309-16.[Abstract/Free Full Text]
- Ettinger WH Jr, Burns R., Messier SP et al. A randomized trial comparing aerobic exercise and resistance exercise with a health education program in older adults with knee osteoarthritis. The Fitness Arthritis and Seniors Trial (FAST). JAMA 1997;277:25-31.[Abstract/Free Full Text]
- Province MA, Hadley EC, Hornbrook MC et al. The effects of exercise on falls in elderly patients. A preplanned meta-analysis of the FICSIT Trials. Frailty and Injuries: Cooperative Studies of Intervention Techniques. JAMA 1995;273:1341-7.[Abstract/Free Full Text]
- Gill TM, Baker DI, Gottschalk M., Peduzzi PN, Allore H., Byers A. A program to prevent functional decline in physically frail, elderly persons who live at home. N Engl J Med 2002;347:1068-74.[Abstract/Free Full Text]
- Testa MA, Simonson DC Health economic benefits and quality of life during improved glycaemic control in patients with type 2 diabetes mellitus: a randomized, controlled, double-blind trial. JAMA 1998; 280:1490-6.[Abstract/Free Full Text]
- Weinberger M., Kirkman MS, Samsa GP et al. The relationship between glycemic control and health-related quality of life in patients with non-insulin-dependent diabetes mellitus. Med Care 1994;32:1173-81.[Web of Science][Medline]
[Order article via Infotrieve]
- Launer LJ, Harris T., Rumpel C., Madans J. Body mass index, weight change, and risk of mobility disability in middle-aged and older women. The epidemiologic follow-up study of NHANES I. JAMA 1994;271:1093-8.[Abstract/Free Full Text]
- Fine JT, Colditz GA, Coakley EH et al. A prospective study of weight change and health-related quality of life in women. JAMA 1999;282: 2136-42.[Abstract/Free Full Text]
- Chao D., Espeland MA, Farmer D. et al. Effect of voluntary weight loss on bone mineral density in older overweight women. J Am Geriatr Soc 2000;48:753-9.[Web of Science][Medline]
[Order article via Infotrieve]
- Williamson DF, Pamuk ER The association between weight loss and increased longevity. A review of the evidence. Ann Intern Med 1993; 119:731-6.[Abstract/Free Full Text]
The British Journal of Diabetes & Vascular Disease, Vol. 5, No. 1,
13-17 (2005)
DOI: 10.1177/14746514050050010301

CiteULike Complore Connotea Del.icio.us Digg Reddit Technorati Twitter What's this?
|
|