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Cardiovascular risk intervention in patients with type 2 diabetes
Mike Masding
Department of Diabetes, Poole Hospital NHS Trust, Longfleet Road, Poole, Dorset, BH15 2JB, UK, mike.masding{at}poole.nhs.uk
Wendy Gatling
The risk of developing vascular disease is greatly increased in people with type 2 diabetes. The use of risk assessment tools is considered. The use of cardiovascular risk tables can underestimate risk by up to 30%. However, multiple risk factor intervention is recognised to be of benefit in reducing vascular risk and treatment strategies should include antiplatelet therapy, a statin and antihypertensive medication.
Key Words: cardiovascular risk type 2 diabetes risk factor assessment.
References
- Conroy RM, Pyorala K., Fitzgerald AP et al. Estimation of ten-year risk of fatal cardiovascular disease in Europe: the SCORE project. Eur Heart J 2003;24:987-1003.[Abstract/Free Full Text]
- Ramsay LE, Haq IU, Jackson PR, Yeo WW, Pickin DM, Payne JN Targeting lipid-lowering drug therapy for primary prevention of coronary disease: an updated Sheffield table. Lancet 1996;348:387-8.[CrossRef][Web of Science][Medline]
[Order article via Infotrieve]
- Dyslipidaemia Advisory Group on behalf of the scientific committee of the National Heart Foundation of New Zealand. 1996 National Heart Foundation clinical guidelines for the assessment and management of dyslipidaemia. NZ Med J 1996;109:224-31.[Web of Science][Medline]
[Order article via Infotrieve]
- Wood D., Durrington PN, Poulter N., McInnes G., Rees A., Wray R. Joint British Recommendations Bon prevention of coronary heart disease in clinical practice. Heart 1998;80(suppl 2):S1-S29.[Free Full Text]
- Guzder RN, Goddard HJ, Mullee MA, Gatling W. Testing the validity of the Framingham equation in Type 2 diabetes: a UK community-based 4-year prospective study. Diabet Med 2002;19(suppl 2):31.
- McEwan P., Williams JE, Griffiths JD et al. Evaluating the performance of the Framingham risk equations in a population with diabetes. Diabet Med 2004;21:318-23.[CrossRef][Web of Science][Medline]
[Order article via Infotrieve]
- Stevens RJ, Kothari V., Adler AI, Stratton IM The UKPDS risk engine: a model for the risk of coronary heart disease in Type II diabetes (UKPDS 56). Clin Sci 2001;101:671-9.[CrossRef][Web of Science][Medline]
[Order article via Infotrieve]
- Song SH, Brown PM Coronary heart disease risk assessment in diabetes mellitus: comparison of UKPDS risk engine with Framingham risk assessment function and its clinical implications. Diabet Med 2004;21: 238-45.[CrossRef][Web of Science][Medline]
[Order article via Infotrieve]
- De Backer G., Ambrosioni E., Borch-Johnsen K. et al. European guidelines on cardiovascular disease prevention in clinical practice. Third Joint Task Force of European and Other Societies on Cardiovascular Disease Prevention in Clinical Practice. Eur Heart J 2003;24:1601-10.[Free Full Text]
- Heart Protection Study Collaborative Group. MRC/BHF Heart Protection Study of cholesterol-lowering with simvastatinin 5963 people with diabetes: a randomised placebo-controlled trial. Lancet 2003;361:2005-16.[CrossRef][Web of Science][Medline]
[Order article via Infotrieve]
- Hall LM, Jung RT, Leese GP Controlled trial of effect of documented cardiovascular risk scores on prescribing. BMJ 2003;326:251-2.[Free Full Text]
- Brady AJB, Betteridge DJ Prevalence and risks of undertreatment with statins. Br J Cardiol 2003;10:218-19.
- Cannon CP, Braunwald E., McCabe CH et al. Intensive versus moderate lipid lowering with statins after acute coronary syndromes. N Engl J Med 2004;350:1495-504.[Abstract/Free Full Text]
- UK Prospective Diabetes Study Group. Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38. BMJ 1998;317:703-13.[Abstract/Free Full Text]
- Hansson L., Zanchetti A., Carruthers SG et al. Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: principal results of the Hypertension Optimal Treatment (HOT) randomised trial. HOT Study Group. Lancet 1998;351:1755-62.[CrossRef][Web of Science][Medline]
[Order article via Infotrieve]
- Gaede P., Vedel P., Larsen N., Jensen GV, Parving HH, Pedersen O. Multifactorial intervention and cardiovascular disease in patients with type 2 diabetes. N Engl J Med 2003;348:383-93.[Abstract/Free Full Text]
The British Journal of Diabetes & Vascular Disease, Vol. 4, No. 6,
414-416 (2004)
DOI: 10.1177/14746514040040060901

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