Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

CiteULike is a free service for managing and discovering scholarly references - click here to get started.

Sign In to gain access to subscriptions and/or personal tools.
The British Journal of Diabetes & Vascular Disease
This Article
Right arrow Abstract Freely available
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Tschoepe, D.
Right arrow Articles by Burchert, W.
Right arrow Search for Related Content
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

Non-invasive imaging for coronary artery disease in diabetes

Diethelm Tschoepe

Heart and Diabetes Center, North-Rhine Westfalia, University Hospital of the Ruhr-University Bochum, Georg Str. 11, 32545 Bad Oeynhausen, Germany, dtschoepe{at}hdz-nrw.de

Wolfgang Burchert

Diabetic patients are at greater risk of cardiovascular disease than non-diabetic individuals, coronary artery disease (CAD) has a less favourable prognosis and is more likely to be silent in diabetic than in non-diabetic patients. Thus, screening is an integral component of risk-reduction strategies for such patients. The available non-invasive testing options include exercise tolerance testing (ETT), stress echocardiography, and stress myocardial perfusion imaging (MPI) with or without gated single-photon emission computed tomography (SPECT). Calcium scoring with electron beam computed tomography (EBCT) and magnetic resonance imaging (MRI) are promising techniques, requiring further validation. Stress MPI with gated SPECT enables assessment of myocardial ischaemia, viability, and function, and allows for risk stratification to improve clinical management in diabetic patients.

Key Words: technetium-99m sestamibi • myocardial perfusion imaging • coronary artery disease • diabetes mellitus non-invasive • risk stratification.

References

  • Murray JL, Lopez AD The global burden of disease. World Health Organization, Geneva, 1996.
  • Rayner M., Petersen S., Buckley C., Press V. Coronary heart disease statistics: diabetes supplement. British Heart Foundation, 2001.
  • American Diabetes Association. Consensus Development Conference on the diagnosis of coronary heart disease in people with diabetes. 10-11 February 1998, Miami, Florida. Diabetes Care 1998;21:1551-9.[Medline] [Order article via Infotrieve]
  • Miettinen H., Lehto S., Salomaa V. et al. Impact of diabetes on mortality after the first myocardial infarction. The FINMONICA Myocardial Infarction Register Study Group. Diabetes Care 1998;21:69-75.[Abstract]
  • Haffner SM, Lehto S., Ronnemaa T. et al. Mortality from coronary heart disease in subjects with type 2 diabetes and in non-diabetic subjects with and without prior myocardial infarction. N Engl J Med 1998;339:229-34.[Abstract/Free Full Text]
  • Evans JMM, Wang J., Morris AD Comparison of cardiovascular risk between patients with type 2 diabetes and those who had had a myocardial infarction: cross sectional and cohort studies. BMJ 2002;324:939-43.[Abstract/Free Full Text]
  • Jacoby RM, Nesto RW Acute myocardial infarction in the diabetic patient: pathophysiology, clinical course and prognosis. J Am Coll Cardiol 1992;20:736-44.[Abstract]
  • Koistinen MJ Prevalence of asymptomatic myocardial ischaemia in diabetic subjects. BMJ 1990;301:92-5.[Abstract/Free Full Text]
  • Cooper S., Caldwell JH Coronary artery disease in people with diabetes: diagnostic and risk factor evaluation. Clin Diabetes 1999;17:58-70.
  • Janand-Dellene B., Savin B., Habib G. et al. Silent myocardial ischemia in patients with diabetes. Diabetes Care 1999;22:1396-400.[Abstract/Free Full Text]
  • International Diabetes Federation. Diabetes Atlas 2003. http://www.idf.org/e-atlas
  • Starkman HS, Cable G., Hala V., Hecht H., Donnelly CM Delineation of prevalence and risk factors for early coronary artery disease by electron beam computed tomography in young adults with type I diabetes. Diabetes Care 2003;26:433-6.[Abstract/Free Full Text]
  • Elkeles R., Flather M., Feher MD et al. Prospective evaluation of diabetic ischaemic heart disease by computed tomography: PREDICT study. Br J Diabetes Vasc Dis 2002;2:69-72.[Abstract/Free Full Text]
  • Mielke C., Shields J., Broemeling L. Coronary artery calcium, coronary artery disease, and diabetes. Diabetes Res Clin Pract 2001;53:55-61.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • O'Rourke RA, Brundage BH, Froehlicher VF et al. American College of Cardiology/American Heart Association expert consensus document in electron beam computed tomography for the diagnosis and prognosis of coronary artery disease. Circulation 2000;102:126-40.[Free Full Text]
  • Task Force of the European Society of Cardiology in collaboration with the Association of European Paediatric Cardiologists. The clinical role of magnetic resonance in cardiovascular disease. Eur Heart J 1998;19:19-39.[Free Full Text]
  • American Diabetes Association. Standards of medical care for patients with diabetes mellitus. Diabetes Care 2002;25:S33-S49.[CrossRef]
  • Vanzetto G., Halimi S., Hammoud T. et al. Prediction of cardiovascular events in clinically selected high-risk NIDDM patients. Prognostic value of exercise stress test and thallium-201 single-photon emission computed tomography. Diabetes Care 1999;22:19-26.[Abstract/Free Full Text]
  • Gibbons RJ, Balady GJ, Mark DB et al. ACC/AHA 2002 guideline update for exercise testing. A report of the American College of Cardiology/ American Heart Association Task Force on Practice Guidelines (Committee on Exercise Testing). Circulation 2002;106:1-60.[Free Full Text]
  • Inzucchi SE Noninvasive assessment of the diabetic patient for coronary artery disease. Diabetes Care 2001;24:1519-21.[Free Full Text]
  • Gianrossi R., Detrano R., Colombo A. et al. Exercise-induced ST depression in the diagnosis of coronary artery disease: a meta-analysis. Circulation 1989;80:87-98.[Abstract/Free Full Text]
  • Cheitlin MD, Armstrong WF, Aurigemma GP et al. ACC/AHA/ASE 2003 guideline update of the clinical application of echocardiography. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (ACC/AHA/ASE Committee to update the 1997 guidelines for the clinical application of echocardiography). Circulation 2003;108:1-90.[Free Full Text]
  • Fleischmann KE, Hunink MG, Kuntz KM, Douglas PS Exercise echocardiography or exercise SPECT imaging? A meta-analysis of diagnostic test performance. JAMA 1998;280:913-20.[Abstract/Free Full Text]
  • Bigi R., Desideri A., Cortigiani L. et al. Stress echocardiography for risk stratification of diabetic patients with known or suspected coronary artery disease. Diabetes Care 2001;24:1596-601.[Abstract/Free Full Text]
  • Leischik R., Kuhlman C., Bruch C. et al. Reproducibility of stress echocardiography using intravenous injection of ultrasound contrast agent (BY 963). Int J Card Imaging 1997;13:387-94.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • Hung MJ, Wang CH, Cherng WJ Can dobutamine stress echocardiography predict cardiac events in nonrevascularized diabetic patients following acute myocardial infarction? Chest 1999;116:1224-32.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • Hennessy TG, Codd MB, Kane G. et al. Evaluation of patients with diabetes mellitus for coronary artery disease using dobutamine stress echocardiography. Coron Artery Dis 1997;8:171-4.[Web of Science][Medline] [Order article via Infotrieve]
  • Klocke FJ, Baird MG, Lorell BH et al. ACC/AHA/ASNC guidelines for the clinical use of cardiac radionuclide imaging - Executive Summary: a report of the American College of Cardiology/American Heart Association Task Force on practice guidelines (ACC/AHA/ASNC Committee to revise the 1995 guidelines for the clinical use of cardiac radionuclide imaging). Circulation 2003;108:1404-18.[Free Full Text]
  • Leppo JA Comparison of pharmacologic stress agents. J Nucl Cardiol 1996;3:S22-S26.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • Heller GV, Shehata AR Pharmacological stress testing with technetium-99m single-photon emission computerized tomography imaging in the preoperative assessment of patients undergoing noncardiac surgery. Am J Card Imaging 1997;10:120-7.
  • Beller GA, Zaret BL Contributions of nuclear cardiology to diagnosis and prognosis of patients with coronary artery disease. Circulation 2000; 101:1465-78.[Free Full Text]
  • Giri S., Shaw LJ, Murthy DR et al. Impact of diabetes on the risk stratification using stress single-photon emission computed tomography myocardial perfusion imaging in patients with symptoms suggestive of coronary artery disease. Circulation 2002;105:32-40.[Abstract/Free Full Text]
  • Hachamovitch R., Shaw LJ, Berman DS The ongoing evaluation of risk stratification using myocardial perfusion imaging in patients with known or suspected coronary disease. ACC Curr J Rev 1999;8:66-71.[CrossRef]
  • Iskander S., Iskandrian AE Risk assessment using single-photon emission computed tomographic technetium-99m sestamibi imaging. J Am Coll Cardiol 1998;32:57-62.[Abstract/Free Full Text]
  • Taillefer R., DePuey EG, Udelson JE et al. Comparative diagnostic accuracy of Tl-201 and Tc-99m sestamibi SPECT imaging (perfusion and ECGgated SPECT) in detecting coronary artery disease in women. J Am Coll Cardiol 1997;29:69-77.[Abstract]
  • Sharir T., Germano G., Kavanagh PB et al. Incremental prognostic value of post-stress left ventricular ejection fraction and volume by gated myocardial perfusion single photon emission computed tomography. Circulation 1999;100:1035-42.[Abstract/Free Full Text]
  • Danias PG, Ahlberg AW, Clark BA 3rd et al. Combined assessment of myocardial perfusion and left ventricular function with exercise technetium-99m sestamibi gated single-photon emission computed tomography can differentiate between ischemic and nonischemic dilated cardiomyopathy. Am J Cardiol 1998;82:1253-8.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • Shaw LJ, Hachamovitch R., Heller GV et al. Noninvasive strategies for the estimation of cardiac risk in stable chest pain patients. Am J Cardiol 2000;86:1-7.[Web of Science][Medline] [Order article via Infotrieve]
  • Kang X., Berman DS, Lewin HC et al. Incremental prognostic value of myocardial perfusion single photon emission computed tomography in patients with diabetes mellitus. Am Heart J 1999;138:1025-32.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • Kang X., Berman DS, Lewin H. et al. Comparative ability of myocardial perfusion single-photon emission computed tomography to detect coronary artery disease in patients with and without diabetes mellitus. Am Heart J 1999;137:949-57.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • Lewin HC, Berman DS, Shaw LJ et al. Noninvasive risk assessment of diabetic and nondiabetic patients with suspected ischemic heart disease. J Am Coll Cardiol 1999;33:447A.
  • Miller TD, Rajagopalan N., Hodge DO et al. The yield of screening stress myocardial perfusion imaging in asymptomatic diabetics. J Am Coll Cardiol 2002;39:163A.
  • Greenland P., LaBree L., Azen SP, Doherty TM, Detrano RC Coronary artery calcium score combined with Framingham Score for risk prediction in asymptomatic individuals. JAMA 2004;291:210-15.[Abstract/Free Full Text]
  • Wackers FJ, Young LH, Inzucchi SE et al. Detection of myocardial ischemia in asymptomatic diabetic subjects: the DIAD study. Diabetes Care 2004, 27:1954-61.[Abstract/Free Full Text]
  • De Backer G., Ambrosioni E., Borch-Johnsen K. et al. European guidelines on cardiovascular disease prevention in clinical practice. Executive summary. Eur Heart J 2003;24:1601-10.[Free Full Text]

The British Journal of Diabetes & Vascular Disease, Vol. 4, No. 4, 245-250 (2004)
DOI: 10.1177/14746514040040040601
Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?



This Article
Right arrow Abstract Freely available
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Tschoepe, D.
Right arrow Articles by Burchert, W.
Right arrow Search for Related Content
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?