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Diabetic MRSA foot infection — role of linezolid therapy

Lukman M Hakeem

K Ann Lockman

Diptendu N Bhattacharyya

Ian W Campbell

Diabetic Department, Victoria Hospital, Kirkcaldy, Fife, KY2 5AH, Scotland UK, jackie.wallace{at}faht.scot.nhs.uk

Diabetic foot ulceration is common and disabling, often leading to amputation of the leg. Foot ulcers commonly become infected and MRSA infection is becoming more prevalent. MRSA is becoming a major public health problem because of its associated high morbidity and mortality, due to difficulty in its eradication with conventional antibiotics. Although vancomycin is the present mainstay of treatment of MRSA infection, a recently introduced antibiotic, linezolid may have benefits. Linezolid can be given orally, obviating the need for i.v. monitoring and offering potential savings in hospital costs with earlier discharge because of its suitability for out-patient eradication of MRSA.

Key Words: diabetes • foot ulcers • infection • MRSA • antibiotics • linezolid.

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The British Journal of Diabetes & Vascular Disease, Vol. 4, No. 1, 44-46 (2004)
DOI: 10.1177/14746514040040010801


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This Article Abstract Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Turner, J. M Articles by Campbell, I. W Search for Related Content Social Bookmarking                         What's this?