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`PROGRESS' in prevention of stroke

Department of Medicine, C7 link, University Hospital, Cardiff, CF14 4XW, guptaabhaya@hotmail..com

PROGRESS (Perindopril pROtection aGainst REcurrent Stroke Study) was an international multicentre trial designed primarily to determine the effects of lowering blood pressure on the risk of recurrent strokes, using perindopril alone or with indapamide, in hypertensive and normotensive patients with and without diabetes. Treatment with perindopril ± indapamide for four years reduced the risk of a further stroke by 28% and cerebral haemorrhage by 50%.

Key Words: stroke • prevention • blood pressure.

References

• Progress Collaborative Group. Randomised trial of perindopril based blood pressure lowering regimen among 6105 individuals with previous stroke or transient ischaemic attack. Lancet 2001;358:1033-41.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
• WHO. World Health Report 1999. Geneva WHO. 1999.
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• Blood pressure lowering treatment Trialist's Collaboration. Effects of ACEI, calcium antagonists and other blood pressure lowering drugs: results of prospectively designed overviews of randomised trials. Lancet 2000;356:1955-64.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
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• Bosch J., Yusuf S., Pogue J. et al. Impact of ramipril and vitamin E on cerebrovascular events in the HOPE (Heart Outcomes Prevention Evaluation) trial. J Am Coll Cardiol 2000;36:suppl A:324A.

The British Journal of Diabetes & Vascular Disease, Vol. 2, No. 1, 27-28 (2002)
DOI: 10.1177/14746514020020011401


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This Article Abstract Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Gupta, A. Search for Related Content Social Bookmarking                         What's this?