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The British Journal of Diabetes & Vascular Disease
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Biochemical hypogonadism in men with type 2 diabetes in primary care practice

Geoffrey I Hackett

Good Hope Hospital, Sutton Coldfield, UK, geoff.hackett{at}virgin.net

Nigel S Cole

Cloisters Practice, Lichfield, UK

Arup A Deshpande

Aldergate Practice, Tamworth, UK

Mark D Popple

Hollies Practice, Tamworth, UK

David Kennedy

Good Hope Hospital, Sutton Coldfield, UK

Peter Wilkinson

Wilkinson Associates, Radnage, Buckinghamshire, UK

Objective:

This study explores the links between testosterone deficiency and Quality Outcomes Framework (QOF) parameters in three south Staffordshire practices prior to a major double-blind placebo-controlled intervention study. Research design and methods:

Four hundred and eighty-eight consecutive type 2 diabetic patients, aged over 18, attending their general practitioner for routine diabetes visits were assessed for sex hormone binding globulin, total testosterone (TT), calculated free testosterone (FT) and bioavailable testosterone, glycated haemoglobin A1c (HbA1c), body mass index, waist circumference, blood pressure, lipid profile, Sexual Health Inventory for Men, and current and past prescriptions for erectile dysfunction (ED).

Results:

TT and FT were significantly inversely associated with raised body mass index, waist circumference and HbA1C. The prevalence of ED was 77%, which was associated with low levels of TT, FT and raised HbA1C. Only 10% were receiving treatment for ED.

Conclusions:

Patients with low testosterone were more likely to fall outside the QOF targets and new markers might be difficult to achieve unless low testosterone is addressed. There is a strong case for the inclusion of TT and FT estimation in routine diabetic care.

Key Words: erectile dysfunction • late onset hypogonadism • Quality Outcomes Framework • Sexual Health Inventory for Men • type 2 diabetes

The British Journal of Diabetes & Vascular Disease, Vol. 9, No. 5, 226-231 (2009)
DOI: 10.1177/1474651409342635
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