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The British Journal of Diabetes & Vascular Disease
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What's this?

Sitagliptin — enhancing incretin action

Ian W Campbell

Diabetic Department, Victoria Hospital, Kirkcaldy, KY2 5AH, Scotland, UK

Caroline Day

Diabetes Research Group, School of Life and Health Sciences, Aston University, Aston Triangle, Birmingham, UK, cday{at}mededuk.com

DPP-4 inhibition offers a new approach to the treatment of type 2 diabetes. Sitagliptin is the first in this new class of agent that lowers hyperglycaemia mainly via enhancing the action of endogenous incretin hormones. Sitagliptin improves glycaemic control with a low risk of hypoglycaemia or weight gain.

Key Words: DPP-4 • gliptin • incretin • inhibitor • sitagliptin • type 2 diabetes

The British Journal of Diabetes & Vascular Disease, Vol. 7, No. 3, 134-139 (2007)
DOI: 10.1177/14746514070070030601
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