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The British Journal of Diabetes & Vascular Disease
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PET scan before CABG in diabetes

Hesham Hegazy

Section of Adult Cardiology; Riyadh and Saud Al-Babtain Cardiac Center, Dammam, Saudi Arabia, leiterl{at}smh.toronto.on.ca

Ayman Refaei

Nuclear Medicine; Riyadh and Saud Al-Babtain Cardiac Center, Dammam, Saudi Arabia

Azza Assedique

Nuclear Medicine; Riyadh and Saud Al-Babtain Cardiac Center, Dammam, Saudi Arabia

Shukri Alsaif

Section of Adult Cardiology; Riyadh and Saud Al-Babtain Cardiac Center, Dammam, Saudi Arabia

Mayada Taha

Internal Medicine; Riyadh and Saud Al-Babtain Cardiac Center, Dammam. Saudi Arabia

Mostafa Refaei

Section of Adult Cardiology; Riyadh and Saud Al-Babtain Cardiac Center, Dammam, Saudi Arabia

Nasser Elkum

Biomedical Statistics; Riyadh and Saud Al-Babtain Cardiac Center, Dammam, Saudi Arabia

Hamed Alomran

Cardiovascular anesthesia; Riyadh and Saud Al-Babtain Cardiac Center, Dammam, Saudi Arabia

Zohair Al-Halees

Cardiac Surgery King Faisal Specialist Hospital and Research Center, Riyadh and Saud Al-Babtain Cardiac Center, Dammam, Saudi Arabia

Background and objectives

Since the role of positron emission tomography (PET) scanning in diabetes is not clear, this study sought to assess the usefulness of PET scanning for viability in this patient group.

Methods

Forty-four per cent insulin-treated, and 56% non-insulin-treated diabetic patients with severely impaired left ventricular function (LVEF 29± 9%) underwent first coronary artery bypass grafting (CABG). Pre-operative viability was assessed by PET scan.

Results

Eighty-two per cent of patients received ≥3 grafts. Twenty-seven patients were discharged home and followed for a mean 3.5±1.6 years. Postoperative LVEF improved to 40±9 (p<0.0001). Multiple regression analysis indicated that the only variable that predicted improvement in global LV function was presence of hibernating segments at PET scan. The single variable that predicted deterioration of LVEF was the number of segments with reduced perfusion and metabolism at PET scan.

Conclusion

PET scan is an accurate tool for prediction of global left ventricular function recovery following CABG in people with diabetes.

Key Words: coronary artery disease • diabetes,impaired left ventricular function • hibernating myocardium • bypass surgery.

The British Journal of Diabetes & Vascular Disease, Vol. 7, No. 1, 32-37 (2007)
DOI: 10.1177/14746514070070010601
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