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The British Journal of Diabetes & Vascular Disease
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Rational therapy of mixed dyslipidaemia in a patient with diabetes

Charles Reasner

University of Texas Health Science Center and Medical Director, Texas Diabetes Institute, 701 S. Zarzamora, San Antonio, TX 78207, USA, Charles.Reasner{at}uhs-sa.com

Diabetic dyslipidaemia refers to the triad of elevated levels of triglycerides and small, dense LDL-C particles and low levels of HDL-C. These lipid abnormalities are largely responsible for the increased risk of cardiovascular complications in patients with diabetes. This case study outlines a rational approach to the treatment of each of these lipid abnormalities and emphasises the importance of both lowering the LDL-C and raising the HDL-C in high-risk individuals. Combination drug therapy will often be necessary to achieve treatment goals in these patients.

Key Words: diabetic dyslipidaemia • atherogenic dyslipidaemia • statins • fibrates • niacin • diabetes.

The British Journal of Diabetes & Vascular Disease, Vol. 7, No. 1, 25-30 (2007)
DOI: 10.1177/14746514070070010501
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