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The British Journal of Diabetes & Vascular Disease
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Mortality rates in hospital patients with hyperglycaemia and MRSA bacteraemia

George I Varughese

University Department of Medicine — ASCOT Centre City Hospital, Dudley Road, Birmingham, B18 7QH, UK

Kostos Miltsios

Department of Anaesthesiology, Rochdale Infirmary, Whitehall Street, Rochdale, OL12 0NB, UK

Harit N Buch

Diabetes Centre, New Cross Hospital, Wolverhampton, WV10 0QP, UK

Jeorge M Orendi

Department of Microbiology, University Hospital of North Staffordshire

John Hb Scarpello

Department of Diabetes and Endocrinology, University Hospital of North Staffordshire, Stoke-on-Trent, ST4 6QG, UK, John.Scarpello{at}uhns.nhs.uk

Methicillin Resistant Staphylococcus Aureus (MRSA) infections in the hospital population have shown a dramatic increase. This pilot study determined whether random/fasting blood glucose measurements were performed on patients admitted to hospital with MRSA bacteraemia. We also examined mortality in relationship to hyperglycaemia, defined as random glucose ≥ 11 mmol/L. Retrospective data for all in-patients aged ≥ 16 years for the three years; 2000—2002 identified 309 patients with MRSA bacteraemia and all of them had laboratory blood glucose concentrations recorded on admission in all cases. A random blood glucose ≥ 11 mmol/L was noted in 129 (42%) patients of whom 82 (64%) died. The mortality was significantly more likely to be in the highest tertile (p<0.05) of blood glucose distributions.

Key Words: MRSA (Methicillin Resistant Staphylococcus Aureus) • diabetes • infection • mortality • hyperglycaemia • bacteraemia.

The British Journal of Diabetes & Vascular Disease, Vol. 6, No. 1, 42-44 (2006)
DOI: 10.1177/14746514060060010501
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