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A prospective study to investigate the incidence of atherosclerotic vascular disease in patients with newly diagnosed type 2 diabetes mellitus

Renal Unit, Walton Building, Glasgow Royal Infirmary, Glasgow, G4 0SF, UK, arthur.doyle{at}gmail.com

Linda M Buchanan

Falkirk Royal Infirmary, Westburn Avenue, Falkirk, FK1 5QE, UK

Shiela Bm Reith

Stirling Royal Infirmary, Livilands, Stirling, FK8 2AU, UK

Allan Bridges

Stirling Royal Infirmary, Livilands, Stirling, FK8 2AU, UK

Type 2 diabetes is associated with premature cardiovascular disease (CVD). We examined the extent of vascular disease and modifiable risk factors in 50 sequential patients with type 2 diabetes, without a previous diagnosis of vascular disease, at their first presentation to a hospital diabetes clinic. Sixty-four per cent of patients were obese (BMI 30). Average HbA1C was 6.8% and mean total cholesterol was 5.74 mmol/L. Forty-seven per cent were hypertensive (systolic pressures 140) and 18% were current smokers.

Eighteen point four per cent of this population had ischaemic heart disease detectable by ECG and exercise ECG. Eighteen per cent had a reduced ankle: brachial pressure index and 49% had carotid atheroma by Doppler scanning.

These findings illustrate the case for aggressive primary vascular disease prevention strategies from the time of diagnosis in type 2 diabetes.

Key Words: diabetes mellitus • atherosclerosis • hypertension • hypercholesterolaemia • ischaemic heart disease.

The British Journal of Diabetes & Vascular Disease, Vol. 5, No. 3, 155-158 (2005)
DOI: 10.1177/14746514050050030801


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