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The British Journal of Diabetes & Vascular Disease
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Review: Hypertension in diabetes: a perspective from clinical pharmacology

Sarah Ross

Department of Clinical Pharmacology, Aberdeen Royal Infirmary, Aberdeen, UK, sarah.ross{at}arh.grampian.scot.nhs.uk

Mary-Joan Macleod

Department of Medicine & Therapeutics, University of Aberdeen, Aberdeen, UK

The treatment of co-existing hypertension is vital to reduce morbidity and mortality from complications of diabetes. There is a vast array of evidence on the subject and the choice of antihypertensive medication is extensive. We have reviewed the evidence for blood pressure (BP) control in diabetes, and examined the evidence to support the use of each class of drug, concentrating on patients without nephropathy or microalbuminuria. Control of BP should be the overriding aim, and requires over time more than one drug in most patients. The weight of evidence suggests that BP-lowering per se is more important than the actual agent used.

Key Words: diabetes • hypertension • antihypertensive therapy • clinical trials.

The British Journal of Diabetes & Vascular Disease, Vol. 3, No. 4, 252-256 (2003)
DOI: 10.1177/14746514030030040301
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